Autocrine/paracrine factors such as steroid and polypeptide hormones, prostaglandins and anti-inflammatory cytokines that are present in the uterine environment during pregnancy re-program their secretory profi
Pregnancy can be viewed as a physical, cardiovascular, immunologic, metabolic, physiological, and psychosocial stress test for the mother whose homeostatic systems are challenged by placental hormones to mostly favor uterine quiescence while providing the fetus with ...
Adipocytes are critical players in maintaining metabolic health, mainly owing to their substantial capacity to take up and store triglycerides and to take up and use glucose in response to insulin (Fig.1). Adipocytes also produce hormones that coordinate metabolic functions, and disruption of these ...
Vitamin B12, or cobalamin, is a vitamin that helps you break down food for energy. Your body uses it to form red blood cells and DNA. You also need it for proper neurological function and to make SAMe, a compound your body needs to make genetic material, proteins, hormones, and fats. ...
A second line should work towards describing the mechanisms by which sexual hormones, especially estrogens, bring on the changes detected in structural and behavioral reorganization. Given the hormonal environment existing during the pregnancy and postpartum period and the interactive nature of these molec...
During the period of maternal recognition of pregnancy (MRP) in the mare, the embryo needs to signal its presence to the endometrium to prevent regression of the corpus luteum and prepare for establishment of pregnancy. This is achieved by mechanical sti
Prostate cancer is the second most common cancer in men globally and is associated with a significant mortality rate. Development of prostate cancer is often driven by male sex hormones called androgens, including testosterone. In patients with mCRPC, their prostate cancer grows and spreads to other...
The ovary ages early in females, with menopause around 50–52 years, much shorter than modern life expectancy of up to 90 years4,5. Ovarian aging, marked by fertility decline and hormonal changes, impacts overall health due to the influence of ovarian hormones on various tissues, such as rep...
Pre pregnancy three major nutrients: Two: Iodine Pre pregnancy than iodine and iodine, the former to promote the next generation of brain development is more significant. Iodine is an essential nutrient for human synthesis of thyroid hormones. However, thyroxine is involved in the proliferation and...
Endocrine disruption typically leads to reproductive system disorders, as hormones are essential for the growth and function of this system [90]. Thus, exposure to endocrine-disrupting herbicides has raised concerns regarding potential adverse effects, as evidenced in Table4. ...