Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen... Ahmad,Nafees 被引量: 0发表: 2000年 HIV-1 reverse transcription. A termination step at the center of the genome. During HIV-1 reverse transcription, the plus-strand of viral DNA is synthesize...
Accumulating evidence has revealed that RCD subroutines are the key features of tumorigenesis, which may ultimately lead to the establishment of different potential therapeutic strategies. Hitherto, targeting the subroutines of RCD with pharmacological small-molecule compounds has been emerging as a ...
coli J5, and Haemophilus influenza, thereby inhibiting the clearance of these pathogens and devastating the infection.44,45 Thus, the exact function of SAP might depend on the features of the specific pathogen. As a potent APP, SAP also directly regulates the function of the innate immune ...
In contrast, stimulation of the NF-κB signalling pathway promotes the polarization to M1 macrophages, while its inhibition promotes the M2 phenotype [26]. Table 1 Comparison between features of classically activated (M1) and alternatively activated (M2) macrophages Full size table To date, fully ...
SEC22B was observed closely related to tumorigenesis with types of mutation. The gene fusion of SEC22B confirmed in aggressive breast cancers and mantle cell lymphoma [39]. EIF3J-AS1 gene was found correlated with prognostic features, including tumour size, vascular invasion and tumour stage, ...
marcescens from rot rhizomes and analyzed its pathogenic features in ginger rhizomes and seedlings and its latent ability to infect mammalian cells. This study provides new information critical to managing ginger diseases caused by bacteria with a cross-kingdom infective cycle....
The statistical power of this experimental design, calculated in RNA-Seq | Power analysis software (https://rodrigo-arcoverde.shinyapps.io/rnaseq_power_calc/), was 0.87. This calculation was performed using the following parameters: Sequencing depth: 87; Sample size: 15; Coefficient of variation...
The ZIM domain, designated as PF06200, is a conserved structural motif situated in the center of the JAZ protein sequence; it contains 28 amino acids and features a distinctive TIF [F/Y] XG sequence adjacent to its N-terminal end [8]. The ZIM domain mediates interaction among JAZ ...
Copenhagen Re, E. coli J5,andHaemophilus influenza, thereby inhibiting the clearance of these pathogens and devastating the infection.44,45Thus, the exact function of SAP might depend on the features of the specific pathogen. As a potent APP, SAP also directly regulates the function of the ...
Importantly, this study pointed to mitochondriopathy and decreased aerobic tricarboxylic acid (TCA) cycle and metabolic functions (processes regulated by ERRα) as key features of UC. In contrast to IBD, colonic ERRα expression is upregulated in colorectal cancer (CRC) and is associated with ...