While the reaction appears to be relatively tolerant to small amounts of tertiary amine bases or weak acids, it stops completely with strong acids. The use of water as an additive had a highly beneficial effect on reactions that were conducted with a stoichiometric ratio of ketone to aldehyde,...
Mechanistic studies and Michaelis鈥揗enten analyses provided insight into the mechanism of the reaction and the impact of active-site mutations on the catalytic properties of the P450. Altogether, these studies demonstrate that engineered P450 variants represent promising biocatalysts for the synthesis of...
aldehyde/ketone (1.0 equiv.). The reaction mixture was stirred at room temperature until complete conversion was observed by TLC. Solvents were removed in vacuo to give the Tosylhydrazone compound. General Procedure B: Tosylhydrazone (0.5 mmol, 1.0 equiv.), Cs2CO3 (0.75 mmol, 1.5 equiv.) and ...
Learn about Grignard reactions with alcohol, ketone, and aldehyde. Study their mechanism and product, and discover which Grignard reaction turns...
The invention concerns dispersions or solutions of a polymerizate, polycondensate or polyadduct formed by a radical reaction and including 0.001 to 20 % by... DR BAUER GERHARD,DR AYDIN ORAL,DR BOTT KASPAR,... 被引量: 3发表: 1993年 New Tyrosinase Inhibitors,(+)-Catechin-Aldehyde Polycondens...
and 5 were obtained by condensation of 3a or 3c with the appropriate aldehyde. Compounds 4b and 5b were cyclized using acetic anhydride to yield the oxadiazolines 6a.b: respectively. Reaction of hydrazide 3a or 3c with 4-toluoyl ... HM Abdel-Bary - Afinidad -Barcelona- 被引量: 4发表: ...
Using L6 as the ligand, we explored the scope of the reaction with respect to the unsymmetrical dialkyl ketone substrate (Fig. 3). First, we tested ketones with primary and tertiary α-carbons (Fig. 3a). Because of the alkyl/alkyl steric repulsion on the same side of the more-substituted...
The present invention, of the compounds of formula I, [Formula 1] Ketone of formula II [2] of And an aldehyde or ketone of formula III, aldehyde or ketone of formula IV [of 3] I refer to compounds of formula I as precursors for. Fragrance, these compounds are useful in functional and...
The invention is directed to a process for the condensation of an aldehyde and a ketone in liquid phase, at a temperature below 60°C in the presence of a modified anionic clay wherein the aldehyde is R1R2R3X-C(=O)H, wherein X is selected from C, Si, Ge, Sn, Pb, N, P, As,...
The reaction involves the activation of a selected aldehyde by converting by iminization to an aldimine or an aminal. The imine group replaces the carbonyl group. The imine C-H bond is then susceptible to attack by a chosen olefin, and hydrolysis to yield the ketone. One moiety of the ...