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The main physiological role of the amplification of ketogenesis during low CHO availability is for KBs to replace glucose as the primary source of fuel for the brain, and to a lesser extent provide an additional substrate for other peripheral tissues such as cardiac and skeletal muscle [1,2,5]...
Hence, our findings underscore the significance of tumor cell glucose metabolism in facilitating tumor-associated cachexia. We observed increased concentration of ketone bodies in tumor cells in comparison to plasma; however, we did not explore any concentrative transport mechanisms. For in vitro studies...
Additionally, glucose concentration was analyzed with the FSP device. For method comparison, the samples were also analyzed in the laboratory by standard methods, which served as the gold standard in our study. A further objective was to evaluate the agreement between samples obtained by minimal ...
During periods of low glucose availability, long-chain fatty acids are partially oxidized to water-soluble four-carbon molecules referred to as ketones, which include acetoacetate (AcAc) and beta-hydroxybutyrate (βHB) [1]. The endogenous production of ketones provides an alternative energy source to...