In dogs, it has a profound effect on cytochrome P450 enzymes, which affects metabolism of other drugs. It is also via the inhibition of steroid P450 biosynthesis that ketoconazole has been used as a short-term treatment for canine hyperadrenocorticism (canine Cushing’s disease). However, for...
For disposal see section 13.SECTION 7: Handling and storage Precautions for safe handling Advice on safe handling Work under hood. Do not inhale substance/mixture. Hygiene measures Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substa...
Ketoconazole also interferes with the adrenal gland’s production of cortisone and can thus be used in the treatment of Cushing’s Disease. For more information on this subject, click here. Ketoconazole is not safe for use during pregnancy and should not be handled by pregnant women.The...