While ketamine is more typically sniffed, we describe a small sample of young ketamine injectors (n = 25) in New York City and highlight risks associated with this emerging type of injection drug use. Our findings indicate that the injection practices, injection groups, and use norms ...
There are also severe side effects of the drug—such as disorientation, confusion, increased blood pressure, and hallucinations, according to theAmerican Addiction Centers. And more, long term impacts are not clear, but there is always the case that somebody can abuse the drug or garner withdrawa...
Individuals with a history of drug abuse or dependence may be at greater risk for abuse and misuse of Ketamine Hydrochloride Injection. Abuse is the intentional, non-therapeutic use of a drug, even once, for its psychological or physiological effects. Misuse is the intentional use, for therapeuti...
the immobilizing and hallucinogenic effects are referred to as being in a “k-hole.” In the context of an illegal, recreational drug, ketamine goes by the street names “K,”“vitamin K,”“super K,”“special K,”“super C,”“special LA coke,”“jet,”“superacid,” and “green.”...
The effects of drugs were expressed as % change (mean ± SEM) from pre-drug baseline, due to the large variability observed from neuron to neuron. The cumulative probability plots of the incidence of various inter-event intervals and amplitude, recorded in control conditions and during drug ...
drug (named Special K, KitKat or Super K) in most countries and is increasingly used by teens and young adults at raves, with the associated risk of addiction and consumption during pregnancy.15,16 It appears, therefore, that the clinical use of ketamine in pediatrics as well as drug- ...
Unfortunately, the usefulness of ketamine for the treatment of depression is limited because of the dissociative, psychotic and abuse properties of this drug.1–4 The antidepressant mechanism of action of ketamine has been proposed to be mediated through non-competitive antagonism at N-methyl-D- ...
Now there is research that has shown that the anesthetic drug Ketamine may have very rapid anti depressant effects. Early work by Rebecca Price and her colleagues (1) revealed that Ketamine acutely reduced suicidal thoughts when patients were assessed 24 hours after a single infusion of the drug...
Study designTypes of cells or animalsSample sizeBiomarkers assessedConditionsChangesDrugType of treatmentDurationEffectsOutcome of depressionReference Cell culture Primary rat mixed glial cell N/A TNF-α, IL-1β, IL-10, TNF-α mRNA, IL-1β mRNA, NF-κB p65 subunit LPS-stimulated ↑ Imipramine,...
In 2019, esketamine nasal spray was approved for TRD in the United State (US) of America and Europe, despite concerns regarding its efficacy and Food Drug Administration (FDA) approval [68]. A recent study utilizing data from the US Food and Drug Adverse Event Reporting System (FAERS) highli...