Learn about the dangers Ketamine abuse, including side effects, street names, and the dangers of mixing ketamine and other drugs.
In a small sample investigation, Walter et al.49 found that MDD patients with high abuse or dependence within the past 3 months, and previous use or treatment with ketamine. The co-occurrence of Axis I anxiety disorders was permitted if this was not the primary cause of illness within the ...
Ketamine treatment must include protections against the abuse liability of ketamine and provide for the management of its acute dissociative effects. Both of these risks may be managed by limiting drug administration to clinical settings. However, alternative treatment approaches, such as home administrati...
In addition to its well-described uses in the fields of anaesthesia, analgesia and drug abuse, ketamine has emerging applications in two other fields. Although it has not been implicated in long-term psychotic reactions in normal subjects, ketamine has been of interest in schizophrenia research for...
For example, one year of esketamine intranasal treatment was not reported to result in cognitive impairment [87] and has not been found to increase the risk of new-onset drug abuse. Nonetheless, 90.1% of patients in the SUSTAIN-2 trial [88] experienced at least one treatment-emergent adverse...
Background and Objectives: Ketamine is a rapid-acting antidepressant with proven efficacy as an add-on agent in unipolar and bipolar treatment-resistant depression. Although many studies have been published, there is still not enough data on the effect o
Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hertfordshire AL10 9AB, UK * Author to whom correspondence should be addressed. † These authors have contributed equally to this work and share first aut...
Ketamine analogues have been emerging in recent years and are causing severe health and social problems worldwide. Ketamine analogues use 2-phenyl-2-aminocyclohexanone as the basic structure and achieve physiological reactions similar to or even more rob