However, within the physiological range these differences offset so that there is no difference in the overall elastic behaviour of the keratoconus and normal corneas. Creep tests at constant load were also performed on normal and keratoconus corneas.Ira...
Rearrangement: In keratoconus, significant changes occur in the collagen lamellae of the anterior stroma compared to a normal cornea. The lamellae in keratoconus are wider and form a smaller angle with the Bowman layer. The affected cornea experiences splitting of stromal lamellae into multiple bundles...
An eye condition in which the cornea bulges outward, interfering with normal vision. Usually both eyes are affected. Mentioned in: Corneal Transplantation Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved. keratoconus (KC) A developmental anomaly in which the ...
Repeatability and reproducibility of corneal epithelial thickness mapping with spectral-domain optical coherence tomography in normal and diseased cornea eyes. Am J Ophthalmol. 2019;197:88–97. Article PubMed Google Scholar Mohr N, Shajari M, Krause D, Kassumeh S, Siedlecki J, Priglinger SG, ...
Keratoconus corneas exhibited more mitochondrial DNA (mtDNA) damage than normal corneas [75]. Keratoconus fibroblasts had increased basal generation of reactive oxygen species and were more susceptible to stressful challenges (low-pH and/or H2O2 conditions) than were normal fibrob- lasts [81]. ...
A subset of several indices (features) is then identified to differentiate between the different severity levels of the disease. The identified features are then employed to create ML models that are pipelined (Fig.2). It is worth noting that the classifying model of normal/KC corneas, as pre...
(Very Asymmetric Ectasia - Normal Tomography), had to meet the criteria of having an ABCD keratoconus-specific grading categorized as stage 0, determined based on assessments of anterior corneal curvature, posterior corneal curvature, pachymetry at the thinnest area of the cornea, and corrected ...
found that levels of oxygen-derived free radicals were higher in the KC cornea than in the normal cornea26. Moreover, Hao et al. demonstrated that ROS and RNS could drive oxidative damage to mitochondrial DNA and affect the oxidative phosphorylation pathway, which resulted in blockage of ...
Relative size of the collagen telopeptides in the human cornea in the normal state and in keratoconusL'Vov K, MDoroshko, A VKalichava, G SSmirnova, N BZiangirova, G G C InSpec
Presence of abnormal elevation on the back corneal surface was reported as a primary sign of early ectatic change in keratoconus and may be used in the differential diagnosis of keratoconic corneas from normal corneas; however, its effectiveness in detecting subclinical forms of keratoconus has not...