判断AKI我们可以通过肌酐和尿量两个指标来看, 今天我们主要提取肌酐。 kidgo指南的表格AKI诊断标准:符合以下情况之一者即可被诊断为AKI:①48小时内Scr升高超过26.5μmol/L(0.3mg/dl);②Scr升高超过基线1.5倍—…
AKI是MIMIC相关研究的常用指标，MIMIC数据库里面AKI诊断按照KIDGO指南，内容太多，今天这个只包括肌酐水平评估：MIMIC数据库里面的基线值并不是一个固定的值而是动态的值。主要涉及ICU住院记录icustays和实验室检查labevents两张表。labevents表里CHARTTIME表示测量时间，VALUENUM表示测量值。icustays表里面intime和outtime分...
●AKI覆盖的肾损伤GFR开始下降 GFR明显异常 WarnockDG.JAmSocNephrol16:3149-3150,2006 2012版KDIGO-AKI诊B疗ie指se南nWVetal.CJASN.2006 KDIGO,2012 AboutAKIguideline •ADQI：2002,RIFLE•AKIN：2005,modifieddefinitionandstagingsystem•KDIGO:2011,FirstclinicalguidelineforAKI –Waitingforpublishedinthissummer...
●AKI覆盖的肾损伤GFR开始下降 GFR明显异常 WarnockDG.JAmSocNephrol16:3149-3150,2006 2012版KDIGO-AKI诊B疗ie指se南nWVetal.CJASN.2006 KDIGO,2012 AboutAKIguideline •ADQI：2002,RIFLE•AKIN：2005,modifieddefinitionandstagingsystem•KDIGO:2011,FirstclinicalguidelineforAKI –Waitingforpublishedinthissummer...
Patients with higher AKI stages experienced more severe/critical COVID-19 (stage 3: 71.0%, stage 2: 44.8%, stage 1: 6.5%; P < .001). The multivariate analysis showed that the proteinuria had the highest relationship with AKI (OR = 6.77 [95% CI: 4.39 to 10.41], P < ...
(AcuteKidneyInjury,AKI)。 ●AKI覆盖的肾损伤 WarnockDG.JAmSocNephrol16:3149-3150,2006 BiesenWVetal.CJASN.2006 GFR正常伴肾脏损伤的标志物改变 GFR开始下降 GFR明显异常 KDIGO,2012 .. AboutAKIguidelineAboutAKIguideline •ADQI:2002,RIFLE •AKIN:2005,modifieddefinitionandstagingsystem ...
AKI stages KDIGO definition (applicable only to people with AKI) AKI stage 1 Serum creatinine and/or urine output criteria AKI stage 2 Serum creatinine and/or urine output criteria AKI stage 3 Serum creatinine and/or urine output criteria Preferred termSuggested abbreviationsaRationale/explanati...
●AKI覆盖的肾损伤GFR开始下降 GFR明显异常 WarnockDG.JAmSocNephrol16:3149-3150,2006 2012版KDIGO-AKI诊B疗ie指se南nWVetal.CJASN.2006 KDIGO,2012 AboutAKIguideline •ADQI：2002,RIFLE•AKIN：2005,modifieddefinitionandstagingsystem•KDIGO:2011,FirstclinicalguidelineforAKI –Waitingforpublishedinthissummer...
Stages defined by creatinine and urine output are surrogates Complications Complications GFR Normal Normal Increased Increased risk risk Damage Damage GFR GFR Kidney Kidney failure failure Death Death Damage Antecedents Intermediate Stage AKI Outcomes Markers such as NGAL, KIM-1, and IL-18 ar...
Stage-based management of AKI: Shading of boxes indicates priority of action—solid shading indicates actions that are equally appropriate at all stages whereas graded shading indicates increasing priority as intensity increases. 3.3造影剂肾病 对具CI-AKI高风险者: ...