The guideline contains chapters on definition, risk assessment, evaluation, prevention, andtreatment. Definition and staging of AKI are based on the Risk, Injury, Failure; Loss, End-Stage Renal Disease (RIFLE) and Acute Kidney InjuryNetwork (AKIN) criter...
The detailed work-up for specif i c causes ofCKD was beyond the scope of the guideline, as were spe-cif i c approaches to acute kidney injury (AKI) and otheracute kidney diseases, diagnostic work-up or treatment ofspecif i c causes of CKD, management of CKD in preg-nancy, detailed ...
•AKIisprevalent;nostandarddefinitionforAKI•AKIisamenabletoearlydetectionandpotentialprevention•AKIimposesaheavyburdenofillness(morbidityandmortality)•CostperpersonofmanagingAKIishigh•Thereisconsiderableclinicalpracticevariabilityinpreventing,diagnosing,treating,andachievingoutcomes•Clinicalpracticeguidelineshave...
Alexander Zarbock, Mira Küllmar ,Marlies Ostermann,et al.Prevention of Cardiac Surgery–Associated Acute Kidney Injury by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: ThePrevAKI-Multicenter Randomized Controlled Trial[J].(Anesth Analg 2021 Aug 01;133(2)). 英文原文?
前瞻性单中心试验表明,在高危患者中实施改善全球肾脏病预后组织(KDIGO)指南显著降低了手术后急性肾损伤(AKI)的发生。我们试图评估在多中心环境下对进行心脏手术的高危患者实施基于KDIGO指南的一系列支持措施的可行性,以为大型确定性试验做准备...
Conclusion In patients of MODS accompanied by AKI, compared using as APACHEⅡscore≤25 as opportune time to start CBP, to commence the treatment in the period of KDIGO standard 1, 2 cannot only improve patient survival with recovery of renal function, but also can reduce the ICU stay and ...
非奈利酮在其他方面也具有良好的耐受性,在2个大型试验中未发现严重AKI的额外风险。更多详情参见KDIGO 2022慢性肾脏病糖尿病管理临床实践指南。 与单独使用SGLT2i和非奈利酮相比,评估SGLT2i和非奈利酮联合使用效果的试验正在进行中(Clin-icalTrials.gov:NCT05254002)。尚未对与无糖尿病的CKD患者进行类固醇和nsMRA的有效...
AKI, acute kidney injury; NSAID, nonsteroidal anti-inflammatory drug. Practice Point 1.2.6: Reduce the dose or discontinue ACEi or ARB therapy in the setting of either symptomatic hypo- tension or uncontrolled hyperkalemia despite the medical treatment outlined in Practice Point 1.2.5, or to...
nostandarddefinitionforAKI•AKIisamenabletoearlydetectionandpotentialprevention•AKIimposesaheavyburdenofillness(morbidityandmortality)•CostperpersonofmanagingAKIishigh•Thereisconsiderableclinicalpracticevariabilityinpreventing,diagnosing,treating,andachievingoutcomes•Clinicalpracticeguidelineshavethepotentialtoreduce...
AKI Acute kidney injury ALMS Aspreva Lupus Management Study ANCA Antineutrophil cytoplasmic antibody APOL1 Apolipoprotein L1 APS Antiphospholipid antibody syndrome ARB Angiotensin-receptor blocker ATN Acute tubular necrosis BMI Body mass index CI Confidence interval ...