The relationship between the IC50 values and the specificity constant, kcat/Km.Katherine, V. WendelsdorfZhuo, SongYang, CaoDavid, C. Samuels
The correlation coefficient was 0.947, indicating that a relationship exists between the kinetic parameters and the stability of the intermediates. The results demonstrate a new method for investigating the catalytic properties of enzymes against any substrates, and a new approach to designing enzymes....