Human kappa opioid receptor gene (OPRK1) polymorphism is associated with opiate addiction. Am J Med Genet B Neuropsychiatr Genet. 2007; 144B (6):771–5.Gerra G,Leonardi C,Cortese E, et al.Human kappa opioid rec
Kappa-opioid receptor (KOR) is a protein that in human is encoded by theopioid receptorkappa 1 (OPRK1) gene (Crowley and Kash, 2015).KORis one of four related receptors that bind opiate-like compounds in the brain and are responsible for mediating the effects of these compounds. These effe...
. Variants of kappa-opioid receptor gene and mRNA in alcohol-preferring and alcohol-avoiding mice.29 Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill Let al. A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence.Hu...
b). Although not at the same position, the serine to cysteine mutation has been reported to improve the stability in both KOR33and δ-opioid receptor (DOR)34. It is worth mentioning that the functional characterization in the cAMP inhibition assay supported that...
Kappa opioid receptor Neurotensin receptor 1 Heterodimerization 1. Introduction The kappa opioid receptor (KOR) and its specific endogenous ligands, dynorphins, are broadly expressed in the central nervous system [1], [2]. Activated KOR plays important roles in the modulation of various physiological...
抗体名:kappa Opioid receptor 浓度:1mg/ml % 靶点:详见说明书 宿主:详见说明书 用途:仅供科研使用 应用范围:WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, 纯度:1mg/ml % 产地:国内 品牌:KEMOBio
KAPPA OPIOID RECEPTOR PAB,产品货号|编号:Invitrogen-44302G,价格及说明书详询!Invitrogen/life technologies(Gibco,Biosource,MP bio,Zymed,Caltag,Dynal) 品牌:美国Invitrogen 正常货期2-3周,部分产品现货 产品留言 标题 联系人 联系电话 内容 点击换一张 ...
英文名称: kappa Opioid receptor/OPRk1 kit 用途: 用于科研实验,不得用于临床 产地: 上海 品牌: 梵态生物 包装规格: 96T 1800元/48T 1200元 标记物: 咨询客服 样本: 血清,血浆,细胞,组织,等相关液体 检测方法: 酶联免疫法 应用: 定量/定性/酶活检测 检测限: 咨询客服 货号: FT-P34131R ...
This chapter describes recent developments in the analysis of kappa opioid receptor (KOR) function at a molecular, cellular and systems level within the central and peripheral nervous system. A combination of neuroanatomical, elec- trophysiological and behavioral techniques have been used to probe the...
The medial prefrontal cortex (mPFC) controls behavior via connections with limbic excitatory afferents that engage various inhibitory motifs to shape mPFC circuit function. The dynorphin (Dyn) / kappa-opioid receptor (KOR) system is highly enriched in the mPFC, and its dysregulation is implicated in...