Universal reference range independent of renal impairment simplifies result interpretation. Correlation of the FLC kappa/lambda ratio produced by N Latex FLC assay is accurate for samples at both high- and low-end concentrations vs. the ratio produced by the FREELITE assay, which can be severely ...
Interpretation of kappa and lambda immunoglobulin light chain staining A pure population of light chain restricted B-cells is easy to recognize using flow cytometricimmunophenotypingand is usually reflected in an abnormal kappa/lambda ratio. However, evaluation of the kappa to lambda ratio will not ide...
KFLC index and CSF KFLC/IgG ratio showed high sensitivity (93% and 86.5%) and moderate specificity (85% and 88%) in diagnosing MS. RIS-CIS patients who converted to MS showed greater KFLC index and CSF KFLC/IgG. Despite OB are confirmed to be the gold-standard to detect intrathecal ...
FLC lambda 8.3–27.0 mg/Land kappa/lambda ratio 0.31–1.56. Protection from falselylow results due to antigen excess is obtained with a built-inpre-reaction in the assay protocols. Lot-to-lot consistency
Kappa free light chain (KFLC), expressed through different interpretation approaches, in patients with radiological or clinically isolated syndrome (RIS-CIS) according to conversion to multiple sclerosis (MS) after a minimum follow up of one year. Mean values were: CSF KFLC/IgG ratio 71.5 (±...
Different mixtures of WPI and KC were prepared by mixing the stock solutions at 1:1 (w/w) WPI: KC mixing ratio and a total biopolymer concentration of 2% (w/w). The mixtures were acidified gradually by the addition of 0.1 M HCl (pH range of 3–7). The optical density (OD) of st...
Here we provide LMS (Lambda-Mu-Sigma)-based continuous pediatric reference percentiles for sRANKL, OPG and sRANKL/OPG ratio that will allow calculation of standardized patient z-scores to assess bone modeling in children. Purpose: Soluble receptor activator of nuclear factor kappa B ligand (s...