CAR-T细胞疗法是近年来推出的新型精准靶向肿瘤治疗技术,2017年美国食品药品监督管理局(FDA)批准了2项以CD19为分子靶标的CAR-T细胞免疫药物上市,用于治疗多种B淋巴细胞白血病,从此开启了细胞免疫治疗的新纪元。经改进的CAR-T免疫疗法也被用来治疗实体瘤、自身免疫疾病、HIV感染和心脏病等疾病,具有广阔的应用空间。 一...
The function of produced CAR-T cells was checked by their ability to kill Daudi cells. X-ray-irradiation inhibited the propagation and viability of K562 cells in a dose- and time-dependent manner. Interestingly, CAR-T-stimulating effectors were remained on the surface of X-ray-irradiated ...
293T细胞株 TF-1细胞 Hela细胞株 胚胎成纤维细胞 产品中心 K562细胞 白血病细胞K562细胞实验 点击放大 产品型号: 产品报价: 1 产品特点: K562细胞 白血病细胞K562细胞实验 通派细胞库:严格无菌操作,鉴定,可传代次数好,附培养操作说明和注意事项。咨询:(K562细胞来源,K562细胞说明书,白血病细胞培养条件,注意事项以及老...
Asano T., Nakamura K., Fujii H., Horichi N., Ohmori T., Hasegawa K., Isoe T., Adachi M., Otake N.,Fukunaga Y.: Altered expression of topoiso- merase IIα contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation. Br. J. Cancer, 2005; 92: 1486-...
结果成功构建6株细胞株:其中1株为阴性对照(K562/sh.eGFP),另5株为CARMAI基因沉默的细胞株。K562/shCARMA1-93对CARMA1的抑制效果最好,利用该模型进行后续研究。台盼蓝拒染法和克隆形成实验表明,l<562/shcARMA1-93的生长和克隆形成能力受到明显抑制(P<0.01)。与空白对照K562和阴性对照K562/sh-eGFP相比,细胞...
(P>0.05).The cytotoxicities against K562 cells by edited NK cells and against the edited K562 cells by NK cells were(24.07± 0.58)% and (16.95±2.00)% at an effector-to-target (E/T) ratio of 20:1, both were lower than the cytotoxicity against K562 cells by NK cells (54.03%±3.46...
23. Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A. et al. Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner. Biochem Bioph Res Co. 2006;342:101-6 24. Tentori L, Ricci-Vitiani L, Muzi A, Ciccarone F, Pelacchi F, Calabrese R. et...
Featured amenities include limo/town car service, express check-in, and express check-out. Planning an event in Las Vegas? This resort has 160000 square feet (14864 square meters) of space consisting of a conference center and meeting rooms. Free self parking is available onsite. Stay in one...
反义寡脱氧核苷酸序列为5TCCCAGCGTGCGOCATC('TT3。正义寡脱氧核苷酸序列为5AGGGATGGCGCACGCTGGTA3,置4"C冰箱保存,使用前用RPMI1640培养液(Gibco)配制所需浓度。加人培养体系中。细胞系的培养K562白血病细胞系由第军医大学珠江医院惠赠。细胞培养于含l0%小牛血清RPMI1640培养液,37℃,5%CO、,饱和湿度条件F培养和...
Lu Y, Pang T, Wang J, Xiong D, Ma L, Li B, Li Q, Wakabayashi S. Down-regulation of P-glycoprotein expression by sustained intracellular acidification in K562/Dox cells. Biochem Biophys Res Commun 2008;377:441-6.Y. Lu,T. Pang,J. Wang,D. Xiong,L. Ma,B. Li,Q. Li,S. ...