Vitamin K is a co-factor in the carboxylation of the bone matrix protein osteocalcin (OC), and thus decreases the concentration of undercarboxylated osteocalcin (ucOC). Animal and in vitro studies suggest that ucOC increases insulin sensitivity. However, epidemiological studies find positive association...
Protecting hearts and bones is an important facet of aging in a healthy way, but it’s a foundation that must be established early. Simply adding a vitamin to one’s daily routine has been clinically proven to do both. Dr. Hogne Vik, Chief Medical Officer with NattoPharma, the world leade...
[7]Koshihara, Y. Vitamin K stimulates osteoblastogenesis and inhibitsosteoclastogenesis in human bone marrow cell culture[J]. Journal ofEndocrinology, 2003, 176(3):339-348. [8]Inaba N , Sato T , Yamashita T . Low-Dose Daily Intake of Vitamin ...
The recommended Daily Value of total vitamin K is 90 mcg for females and 120 mcg for males. However, that may not be enough to reach optimal levels of K2 for some people. Your body recycles vitamin K, but it stores very little. So, it can be depleted rapidly if it isn’t replaced ...
aspects of glucose and energy metabolism in type 2 diabetes.MethodsThirty adult male rats were allocated equally into five groups: control group, diabetes mellitus group, and groups 3, 4, and 5, which received Vit K2 at three daily dose levels (10, 15, and 30mg/kg, respectively) for 8...
This a good daily supplement to add on to multivitamins. Arthur Was told to take K2 with vitamin D3. I am very satisfied with this product. Reeveston, Eaton, IN Must have with calcium. Blaz, FL I use it to supplement calcium for bone strength. ...
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vitamin K2 is commonly deficient; even in all healthy humans tested, a significant percentage of the extra-hepatic VKD proteins, which are activated by vitamin K2, e.g., osteocalcin and matrix Gla-protein, are only partly carboxylated and therefore inactive. Increasing vitamin K intake has...
Vitamin K2 [as menaquinone-4 (45 mg)]45,000 mcg Other ingredients: microcrystalline cellulose, gelatin (capsule), vegetable stearate, silica. Non-GMO Dosage and Use Take one (1) capsule daily with food, or as recommended by a healthcare practitioner. ...
(NOAEL) was determined to be 4500 mg/kg/d, the maximum dose tested. For the evaluation of genotoxicity, reverse mutation, chromosomal aberration, and micronucleus tests were performed. In the reversion mutation test, vitamin K2 did not induce reversion in bacterial strains, and no chromosomal ...