Our studies have also shown for the first time that E2F1 can be modified by K11-linkage specific ubiquitin chain formation (Ub-K11). The formation of Ub-K11 chains on E2F1 is increased in the presence of Cdh1 and accumulated in the presence of proteasome inhibitor, suggesting that APC/CCdh1...
Our studies have also shown for the first time that E2F1 can be modified by K11-linkage specific ubiquitin chain formation (Ub-K11). The formation of Ub-K11 chains on E2F1 is increased in the presence of Cdh1 and accumulated in the presence of proteasome inhibitor, suggesting that APC/C...
摘要: K11-linked diubiquitin adopts a conformation distinct from other diubiquitins A K11-linked polyubiquitin-specific antibody was engineered UbcH10/Ube2S and APC/C are the major source of mitotic K11-linked chains invivo K11-linked chains act as proteasomal degradation signals invivo关键词:...
品名: MABS107-I | Anti-Ubiquitin K11 linkage Antibody, clone 2A3/2E6 规格: 100 µL 产品描述: This Anti-Ubiquitin K11 linkage Antibody, clone 2A3/2E6 is validated for use in western blotting & ICC for the detection of Ubiquitin K11 linkage. 商品评论 商品评分 ///... 0 0人评...
Moreover, we co-transfected SAG-CUL1, followed by in vivo ubiquitylation assay, to determine whether the K11 linkage is SAG specific. Indeed, SAG-CUL1 can also promote polyubiquitylation of β-TrCP1 and β-TrCP1ΔF when wild type or K11 ubiquitin mutant, but not other mutants, was used ...