信息来源:Switching to dolutegravir plus rilpivirine versus maintaining current antiretroviral therapy regimen in virologically suppressed people with HIV-1 and the Lys103Asn (K103N) mutation: 48-week results from a randomised, open-label pilot clinical trial Published:March, 2024DOI:doi.org/10.1016/S...
(2023). Efficacy of dolutegravir and rilpivirine for treatment-naive HIV-1-infected individuals with K103N resistance mutation: a multicentre, open-label, randomised phase 2b trial. The Lancet HIV, 10, e466-e474. O网页链接2、文中部分内容或图片来源网络,如有侵权,请联系删除。
Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature. J Med Case Rep. 2009; 3 :9132. http://dx.doi.org/10.4076/1752-1947-3-9132 ....
Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature. J Med Case Rep. 2009; 3 :9132. http://dx.doi.org/10.4076/1752-1947-3-9132 ....
Sensitive detection of the K103N non-nucleoside reverse transcriptase inhibitor resistance mutation in treatment-naive HIV-1 infected individuals by rolling circle amplification. J Virol Methods. 2009;161(1):128-35.Wang B, Dwyer DE, Chew CB, Kol C, He ZP, Joshi H, Steain MC, Cunningham AL...
Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. J. Acquir. Immune. Defic. Syndr. 38:37-42.Detection of minority populations of HIV-1 expressing the K103N resistance mutation in patients failing nevirapine. Lecossier D,Shulman N...
After treatment, the M184V mutation occurred less frequently among sdNVP-exposed women than among sdNVPunexposed women, but the frequency of NNRTI-associated mutations was similar between these groups of women with inadequate virologic response. Conclusions: Exposure to sdNVP in the prior 18-36 ...
HIV MedRokx C, et al. Successful switch to rilpivirine/tenofovir/emtricitabine in HIV-1-infected patients with an isolated K103N mutation acquired during prior nonnucleoside reverse transcriptase inhibitor therapy. HIV Medicine 15: 611-614, No. 10, Nov 2014. Available from: URL: http://....
Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D. J Mol Diagn 2006; 8(4): 430-2.Church JD, Jones D, Flys T, et al.: Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N ...
Virus mutationThe structural rearrangement due to the unbinding of HBY 097 in K103N mutant HIV-1 reverse transcriptase ( RT ) was studied using two nanosecond molecular dynamics simulations. The simulations showed the dynamics of an open or upright position of the p66 thumb subdomain moving to ...