提供的JMJD1A单克隆抗体, 克隆号2E1产品克隆号为2E1,对应的亚型为IgG1。该基因又称DKFZp686A24246|DKFZp686P07111|JHDM2A|JHMD2A|JMJD1|KDM3A|KIAA0742|TSGA,全名为jumonji domain containing 1A,对应Gene号为,其蛋白编号为。 应用类型 ELISA,WB-Ce,IF ...
Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem. 2010; 285: 2758-2770.Liu Z, Zhou S, Liao L, et al. Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element ...
At the molecular level, b-adrenergic stimulation induces binding of JMJD1A to the uncoupling protein 1 gene (Ucp1) whose product is pivotal for heat generation. This b-adrenergic-induced binding of JMJD1A to a proximal Ucp1 enhancer region is a critical step for subsequent gene activation; ...
Cited in 41 publications. KDM3A,JMJD1A antibody for WB, IHC, IF/ICC, IP, ELISA and reacts with human.
Disruption of the Jmjd1a gene in mice significantly increased H3K9me1 and H3K9me2 levels in pachytene spermatocytes and early elongating spermatids without affecting H3K9me3 levels. Concurrently, the levels of histone acetylation were decreased in Jmjd1a knock-out germ cells. This suggests Jmjd1a ...
It was also shown that STAT3 could bind to the promoter region of Jmjd1a gene. These data demonstrate that Jmjd1a might be a critical signaling molecule underlying the maintenance of pluripotency in mES cells. 展开 关键词: Animals Humans Mice Cell Line Oxidoreductases, N-Demethylating Nuclear ...
Entrez Gene ID:(Human) 55818 功能 transcription regulatory region sequence-specific DNA bindingcore promoter bindingtranscription factor activity, sequence-specific DNA bindingiron ion bindinghistone demethylase activityandrogen receptor bindingdioxygenase activityhistone modifying enzyme ...
Entrez Gene ID: (Human) 55818 功能 transcription regulatory region sequence-specific DNA binding core promoter binding transcription factor activity, sequence-specific DNA binding iron ion binding histone demethylase activity androgen receptor binding dioxygenase activity histone modifying enzyme 参与通路 ...
Notably, thetumor suppressor gene was stimulated by JMJD1A and MDFIC, but not by MDFI, and HIC1 overexpression phenocopied the growth suppressive effects of MDFIC in HCT116 cells. Similar to colorectal cancer,was up- anddownregulated in breast, ovarian and prostate cancer, but both were ...
Target NameJMJD1A Alternative NamesLysine-specific demethylase 3A, KDM3A, JHDM2A, JHMD2A, TSGA Accession No.Swiss-Prot:Q9Y4C1 Gene ID:55818 UniprotQ9Y4C1 Gene ID55818; Concentration1mg/ml FormulationSupplied in PBS containing 0.02% sodium azide. ...