A family of Jumonji C (JmjC)-domain-containing histone demethylases was shown to contain a sequence fragment closely homologous to DSIP. One type of these ubiquitous and phylogenetically ancient proteins encoded by JMJD1B gene includes the WKGGNASGE sequence that differs from DSIP by only 2 ...
Several JmjC-domain-containing proteins have been functionally implicated in inherited disease and cancer, indicating that these enzymes have important roles in cellular homeostasis and might be suitable targets for therapeutic intervention. Abstract
4、these proteins, JmjC domain only family contains seven proteins with JmjC domains only. Except for OsJMJ760, the functions of the other members are unclear. In th.【关键词】JmjC蛋白 组蛋白去甲基化修饰 水稻根系【英文关键词】JmjC domain containing protein Histone demethylase Rice root【索购全文...
【关键词】JmjC蛋白组蛋白去甲基化修饰水稻根系【英文关键词】JmjCdomaincontainingproteinHistonedemethylaseRiceroot 【索购全文】联系Q1:138113721Q2:139938848【目录】OsJMJ714在水稻侧根发育中的功能分析6-712-19 ABSTRACT73 缩略词表11-12 摘要 第一章引言 1.1.1 1.1植物组蛋白甲基化研究进展12-16 组蛋白修饰1212...
JmjC-domain-containing proteins and histone demethylation 2006, Nature Reviews Genetics Histone demethylation by a family of JmjC domain-containing proteins 2006, Nature The diverse functions of histone lysine methylation 2005, Nature Reviews Molecular Cell Biology Oxygen sensing by HIF hydroxylases 2004,...
Among of these proteins, JmjC domain only family contains seven proteins with JmjC domains only. Except for OsJMJ760, the functions of the other members are unclear. In th... 【关键词】JmjC蛋白组蛋白去甲基化修饰水稻根系 【英文关键词】JmjC domain containing protein Histone demethylase Rice root...
The Jumonji C domain-containing family of histone lysine demethylases (Jumonji KDMs) have emerged as promising cancer therapy targets. These enzymes remove... L Duan,RE Perez,S Calhoun,... - 《Cancer Biology & Therapy》 被引量: 0发表: 2022年 Chapter 8 Inhibitors of JmjC-containing Histone ...
Jumonji (JmjC) domain proteins are known regulators of gene expression and chromatin organization by way of histone demethylation. Chromatin modification and remodeling provides a means to modulate the activity of large numbers of genes, but the importan
The jumonji C (JmjC)-domain containing proteins are an extending family of redox enzymes that catalyse a wide range of oxidation reactions. These proteins are found in all living organisms and are characterised by sharing the highly conserved JmjC domain. This domain was first described by Takeuchi...
Jumonji domain-containing proteins are a family functioning as histone demethylase. Jumonji domain-containing protein 8 (JMJD8) is Jumonji C (JmjC) domain-only member of this family, and its physiological functions remain largely unknown. In this study, we investigated the mechanism by which ...