select article Phosphorylation of Troponin I finely controls the positioning of Troponin for the optimal regulation of cardiac muscle contraction Research articleAbstract only Phosphorylation of Troponin I finely controls the positioning of Troponin for the optimal regulation of cardiac muscle contractio...
成果发表在著名学术期刊Circulation Research。论文题目为“Loss of cardiac Ferritin H facilitates cardiomyopathy via Slc7a11-mediated ferroptosis” 【5】。 王福俤/闵军霞团队发现药物金诺芬通过抑制硫氧还蛋白还原酶TXNRD导致细胞膜脂质过氧化累积,并最终引发铁死亡。该成果首次将TXNRD蛋白引入到铁死亡调控网络。这也是...
事实证明,心脏电生理标测(Mapping of cardiac electrophysiology)在促进我们对心脏疾病的了解和临床诊疗方面发挥着关键作用。相机技术、3D 打印和其他领域的发展在临床使用标测系统在空间分辨率和整体功能方面不断提升,以及光学标测等临床前技术的改进方面发挥了巨大作用。即便如此,我们对心律失常等心脏疾病的了解以及这些标...
Pavlovic is an Associate Professor and leads the Cardiac Diseases Theme at the University of Birmingham (UK). His primary research interest is to understand molecular mechanisms of ion transport in the heart and how these may be targeted to treat cardiovascular disease. His work is translational ...
作者: JN Weiss,A Garfinkel,HS Karagueuzian,TP Nguyen,Z Qu 展开 摘要: Fibrosis is known to promote cardiac arrhythmias by disrupting myocardial structure. Given recent evidence that myofibroblasts form gap junctions with myocytes at least in co-cultures, we investigated whether myofibroblast-myocyt...
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