Endosomal TLRs (effectors of innate immunity) are also involved (but differently) in the 3 conditions, further suggesting viral involvement, although TLR activation could be secondary to tissue damage.doi:10.1038/nrrheum.2016.97OnuoraSarahNature Reviews Rheumatology...
"Although it was previously known that certain clinical features of JDM correlated with MSA subtypes, any correlations between muscle pathology and MSA subtypes were unknown before this study," recalls Deakin.doi:10.1038/nrrheum.2016.97Sarah OnuoraSpringer NatureNature Reviews Rheumatology...