0854 The sensitivity of JC virus DNA detection vs JC virus antibody testing in a natalizumab-treated group of relapsing MS patientsNatalizumab treatment for relapsing remitting multiple sclerosis (RRMS) is associated with a risk of progressive multifocal leukoencephalopathy (PML) due to reactivation of ...
摘要: Anti-JC virus (JCV) antibody index is the predictive factor of progressive multifocal leukoencephalopathy (PML) for multiple sclerosis (MS) patients treating with natalizumab. The aim of this study...关键词: Multiple sclerosis JC virus Natalizumab Anti-JCV antibody positivity and index ...
associatedwiththepresenceofanti–JCvirus(JCV)antibodies.Weanalyzedwhetheranti-JCVantibodylevels,meas- uredasindex,mayfurtherdefinePMLriskinseropositivepatients. Methods:Theassociationbetweenserumorplasmaanti-JCVantibodylevelsandPMLriskwasexaminedinanti-JCV ...
This conclusion was supported by another recent nested case-control study147 in which IgG antibody to JC virus was measured in 611 colorectal cancer cases, 123 adenomatous polyp cases, and matched controls. There was no association between antibodies to JCV and colorectal cancer, with OR 0.91 (...
JC virus (JCV) is the causative agent of the demyelinating disease progressive multifocal leucoencephalopathy (PML), which can be diagnosed by detection in the cerebrospinal fluid (CSF) of both JCV DNA and intrathecally-produced anti-JCV antibody. However, the restricted in-vitro species and cell...
Conclusion Immunoreactivity for p53 protein is more common in anaplastic medulloblastomas, ATRT and sPNET than in non-anaplastic tumors, and is associated with worse clinical outcomes. However, JC virus infection is not responsible for increased levels of p53 protein.View...
Results: Pre-pandemic anti-JCV antibody serostatus change was observed for 7.4%–7.7%. During the first and second years of the pandemic, 7.3% and 7.2% of patients' serostatus changed, respectively. Conclusion: The proportion of patients with anti-JCV antibody serostatus change did not ...
CD30 is expressed in anaplastic large cell lymphoma (ALCL), Hodgkin lymphoma (HL), lymphomatoid papulosis (LyP), mycosis fungoides (MF), follicle center cell lymphoma (FCL) and Epstein-Barr virus (EBV)-associated lymphomas. Brentuximab vedotin (BV) is ananti-CD30 monoclonal antibody, conjugated...
The Venereal Disease Research Laboratory test revealed serum positivity (1:512), and the fluorescent treponemal antibody absorption test was reactive. 阳了! 06 有毒的肺梅毒 考虑肺梅毒:pulmonary syphilis。 青霉素DuangDuangDuang的搞上去! 07 A chest CT p...
Accordingly, an analytically validated assay that uses a highly purified VP1-containing virus-like particle (VLP) has been developed to detect the presence of JCV antibody in a body fluid, such as serum, plasma, urine, CSF, or other body fluid that contains antibodies. In experiments to valida...