Objective: To assess changes in the proportion of patients who converted to a positive anti-JC virus (JCV) antibody (Ab) serostatus before and during the COVID-19 pandemic.Background: Natalizumab, approved to treat relapsing MS, is associated with increased risk of progressive multifocal ...
Cat No.13101-1-AP Freight/Packing:-- Country/Region Please contact our China branch Proteintech Guarantee Request bulk or custom quote humanWB A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum. ...
J Frisque Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA Alternative splicing of the JC Virus (JCV) precursor early mRNA yields ve transcripts that encode proteins that regulate the life cycle of this human poly- omavirus. Large...
The disclosure relates to methods and reagents for analyzing samples for the presence of JC virus antibodies. Disclosed is a method that includes obtaining a biological sample from
VP-Antigene des JC-Virus German Patent DE19543553 Kind Code: B4 Abstract: The invention concerns new virus-like particles composed of the VP1 protein of the JC virus, a process for their production and their use in analytical, diagnostic and therapeutic methods....
摘要: A review is offered for the article "JC virus in CD34+ and CD19+ cells in patients with multiple sclerosis treated with natalizumab" by E. M. Frohman, published in the 2014 issue of "JAMA Neurology."年份: 2014 收藏 引用 批量引用...
In support of these data, JCV tAg also suppressed RIG-I(2CARD)-induced transcript induction of CCL5 and OAS1 with a potency similar to that of the influenza A virus (IAV) NS1 protein, which is a bona fide viral antagonist of RIG-I signaling and thus served as a positive control (44...
Daniel DC, Kinoshita Y, Khan MA, Del Valle L, Khalili K, Rappaport J, Johnson EM (2004) Internalization of exogenous human immunodeficiency virus-1 protein, Tat, by KG-1 oligodendroglioma cells followed by stimulation of DNA replication initiated at the JC virus origin. DNA Cell Biol 23:858...
Anti-JC virus antibody levels in serum or plasma further define risk of natalizumab-associated progressive multifocal leukoencephalopathy. Objective The increased risk of progressive multifocal leukoencephalopathy (PML) with natalizumab treatment is associated with the presence of anti–JC virus (JCV) antibod...
JC virus (JCV) Agnoprotein (Agno) plays critical roles in successful completion of the viral replication cycle. Understanding its regulatory roles requires a complete map of JCV-host protein interactions. Here, we report the first Agno interactome with host cellular targets utilizing “Two-Strep-Tag...