本研究结果显示,IL-10可促进正常宫颈上皮细胞增殖、迁移及侵袭,JAK1、TYK2、STAT3及下游与细胞侵袭相关的MMP-9在IL-10过表达组细胞中高表达,而加JAK1/TYK2抑制剂PF06700841后,IL-10的作用被阻断。表明IL-10通过JAK1/TYK2/STAT3通...
JAK1STAT3Genetic susceptibilityMDRRabbitTyrosine kinase 2 (TYK2), Janus kinase 1 (JAK1), and signal transducer and activator of transcription 3 (STAT3) all play critical roles in innate and acquired immunity. In this study, we investigated the association between the TYK2, JAK1, and STAT3 ...
STAT3GeneticsusceptibilityMDRRabbitTyrosine kinase 2 (TYK2), Janus kinase 1 (JAK1), adoi:10.1016/j.livsci.2015.08.014LaiSichuanSong-JiaSichuanFuSichuanLuSichuanChenSichuanShi-YiSichuanJiaSichuanXian-BoSichuanZhaoSichuanMing-DeSichuanNSTLLivestock Science...