红斑狼疮患者皮损组织及外周血单核细胞中JAK-STAT1信号转导通路的活化和抑制表达均存在异常.rHMGB1可能部分通过JAK-STAT1信号转导途径的异常调控介导了红斑狼疮的炎症损伤.%Objective To study the activation of Janus protein tyrosine kinase (JAK)/signal transducer and activator of transcriptio...