The Jackson Laboratory Repository (JAX) serves as a centralized facility for the development, distribution and cryopreservation of mouse models of human biology and disease. JAX distributes more than 10,500 strains to the scientific community, many with applications in immunology research, including ...
And before the drug trials in patients, research using mouse models of provided the essential foundation of knowledge of the mechanisms of SMA. Thirteen years ago, the SMA Foundation asked The Jackson Laboratory (JAX) to distribute mouse models of the disease to the biomedical ...
Charles Lee, Ph.D., FACMG. "We are thrilled to collaborate with LG AI Research to unleash the immense potential of AI in creating a data science bridge between humans and mouse models, which will advance our ability to predict human diseases and help in the d...
The Jackson Laboratory Repository serves as a centralized facility to import, develop, preserve, and distribute mouse models to the scientific community. Approximately 300 strains are added annually to one of the largest collection of characterized mouse strains available. New models of increased tumor ...
Dr. Clarence Cook Little, a Harvard-trained geneticist and former president of the University of Maine, founded the Laboratory in 1929 as a cancer research center. His study of cancer convinced him that mouse models held the key to understanding the genetic basis of human development, diseases,...
Genomes of the mouse Collaborative Cross. Genetics. 2017;206(2):537–56. https://doi.org/10.1534/genetics.116.198838. Article CAS PubMed PubMed Central Google Scholar Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, et al. Aging research using mouse models. ...
CRE-LOXP基因敲除系统(JACKSONLAB)
The site contains several databases concerning the genetics and biology of the laboratory mouse. The Jax Mice database contains lists of mouse models and describes over 2000 strains of genetically defined mice for biomedical research.The Mouse Genome Informatics (MGI) database provides access to ...
Scrambler, Fidget, Stargazer, and other mouse strains that mimic human neurological diseases, may have to move over. They are about to get plenty of company in their home in Bar Harbor, Maine. The Jackson Laboratory is planning to use its largest grant e
Jackson Laboratory在 周四, 05/12/2022 - 12:32 提交 Cat Lutz, Ph.D.The primary research goals of the Lutz lab involve developing preclinical mouse models of neurodegeneration to test therapeutics and inform clinical trials.Cat Lutz, Ph.D., M.B.A. was recently named vice president ...