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2022.The radiosensitizing effect of β-Thujaplicin, a tropolone derivative inducing S-phase cell cycle arrest, in head and neck squamous cell carcinoma-derived cell lines. Invest New Drugs.https://doi.org/10.1007/s10637-022-01229-3
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We also found that angiogenesis inhibitors and asparaginase reduce tumor growth in a TSC2 tumor mouse model and although these drugs are not as effective as rapamycin, these drug classes may have some therapeutic potential in the treatment of TSC related tumors. Background Tuberous Sclerosis Complex...
Enzyme inhibition activity of 10 mg/mL sample solutions was analysed in vitro using spectrophotometric methods adapted to 96-well plates. Drugs already on the market were used as a reference: acarbose (10 mg/mL, anti-diabetic drug), arbutin (1 mg/mL, tyrosinase inhibitor), galantamine (1 mg...