Interaction of factor IXa with factor VIIIa. Effects of protease domain Ca2+ binding site, proteolysis in the autolysis loop, phospholipid, and factor X. J Biol Chem 1997; 272: 23418-26.Mathur A, Zhong
凝血过程中激活X因子生成Xa的物质是()。A.PF3B.VIIIa因子C.IXa、VIIIa因子、PF3及Ca2+组成的复合物D.Ca2+
The intrinsic tenase (Xase) complex, formed by factors (f) VIIIa and fIXa, forms on activated platelet surfaces and catalyzes the activation of factor X to Xa, stimulating thrombin production in the blood coagulation cascade. The structural organization of the membrane-bound Xase complex remains...
凝血因子缺乏症血友病A获得性因子 VIII缺乏症+ [1] 非在研适应症- 原研机构 Chugai Pharmaceutical Co., Ltd. 在研机构 Hoffmann-La Roche, Inc.罗氏(中国)投资有限公司Roche Registration Ltd. + [7] 非在研机构- 最高研发阶段批准上市 首次获批日期 ...
百度试题 题目肝素增强抗凝血酶III灭活下列哪组凝血因子A.IIa、VIIa、IXa、Xa、XIIaB.IIa、IIIa、IVa、Va、VIIaC.IIa、VIa、VIIa、VIIIa、IXaD.IIa、VIIa、VIIIa、IXa、XaE.IIa、VIIa、VIIIa、Xa、XIIa 相关知识点: 试题来源: 解析 A 反馈 收藏
Emicizumab, a humanized bispecific antibody to coagulation factors IXa and X with a factor VIIIa-cofactor activityEmicizumab, a humanized bispecific antibody to coagulation factors IXa and X with a factor VIIIa-cofactor activityBispecific antibodyEmici...
Hemophilia A is a bleeding disorder resulting from coagulation factor VIII (FVIII) deficiency. Exogenously provided FVIII effectively reduces bleeding complications in patients with severe hemophilia A. In approximately 30% of such patients, however, the 'foreignness' of the FVIII molecule causes them ...
百度试题 题目利伐沙班的作用机制是直接抑制()因子 A.XaB.VIIIC.IIID.IXa相关知识点: 试题来源: 解析 A 反馈 收藏
Novel agents that inhibit the interaction of factor VIIIa with factor IXa in newly discovered regions of interaction, Region 2 and Region 3, are disclosed. The novel polypeptides or derivatives of polypeptides prevent activation of factor X and have anti-coagulation activity. The agents include ...
Novel agents that inhibit the interaction of factor VIIIa with factor IXa in newly discovered regions of interaction, Region 2 and Region 3, are disclosed. The novel polypeptides or derivatives of polypeptides prevent activation of factor X and have anti-coagulation activity. The agents include ...