This allowed dissecting the new molecules into the single portions influencing the zinc chelation properties and the selectivity profile thereby offering a new platform for the discovery of new isotype selective CA inhibitors.doi:10.1016/j.ejmech.2021.113490Silvia Salerno a...
This allowed dissecting the new molecules into the single portions influencing the zinc chelation properties and the selectivity profile thereby offering a new platform for the discovery of new isotype selective CA inhibitors. (C) 2021 Elsevier Masson SAS. All rights reserved.Salerno, SilviaAmendola, ...
More significant antitumoral effects could be observed for the free H2Lph ligand, agreeing with the antimicrobial results. Hence, the antitumor study demonstrated the influence of the central metal ion on Tweedy’s chelation effect to the bioaction of H2Lph in its coordinated form with VO2+ ...