符合方案集分析（Per-Protocol Analysis, PP）则是FAS的子集，仅包括那些在入排标准、治疗过程和关键指标测量上严格遵循研究方案的参与者。尽管PP集可能更严格，但与FAS相比，差异通常不大。在实际研究中，研究者可能会选择报道FAS或PP分析，配合ITT一起，以提供更全面的评估。总的来说，RCT的这三个分析...
分析,同时应用意向性分析(Intention-to-treat analysis,ITT分析)和符合方案集分析(Per-protocol analysis,PP分析)两种方法.结果:共纳入14项RCT,合计6 058例患者.PP... 陈丽金 - 《中国药房》 被引量: 22发表: 2016年 伏诺拉生联合高剂量阿莫西林二联方案根除幽门螺杆菌的疗效 按意向性分析(ITT)和符合方案集分析...
4. 安全集(Safe analysis Set,SS) 安全集与上述几种评价疗效的数据集不同。安全集是用来评价试验药物安全性的。 一般要符合以下三点:1)随机化分组;2)至少使用过一剂试验药物;3)至少有一次安全性评价。 所以,开头提到的用了一次药就产生了不良反应的张大爷也要纳入安全集里进行分析。 三、不同数据集的关系以...
doi:10.1016/j.jalz.2009.05.488CristinaSampaioSDOSAlzheimers & Dementia
为了解决上述真实遇到的问题,统计学家引入了两种统计分析方式:意向性分析(Intention-to-treat, ITT)和 符合方案分析(Per-Protocol, PP)。 1、意向性分析ITT:指的是对所有随机化的病人进行随访、评价和分析,而不管其是否依从计划的治疗过程。这种保持初试随机化的做法对于防止发生偏倚是非常有益的,并且为统计学检验...
Perceptions of an HIV self-testing intervention and its potential role in addressing the barriers to HIV testing among at-risk heterosexual men: a qualitative analysis. Sexually transmitted infections. 2021;97(7):514–20. Article PubMed Google Scholar Wirtz AL, Naing S, Mon SHH, Paing AZ, ...
Perceptions of an HIV self-testing intervention and its potential role in addressing the barriers to HIV testing among at-risk heterosexual men: a qualitative analysis. Sexually transmitted infections. 2021;97(7):514–20. Article PubMed Google Scholar Wirtz AL, Naing S, Mon SHH, Paing AZ, ...
e ANCOVA analysis of heat production per body weight of mice. f, g GTT (f) and insulin tolerance test (ITT; g) in control (CTL) and iKO mice after 12 weeks of CD or HFD treatment. AUC of GTT and AAC of ITT in the right panels. CTL-CD: n = 5, iKO-CD: n = 6, CTL-HFD...
Thermal cycling and melting curve analysis. The FRET-qPCR for Chlamydia spp. was performed in a LightCycler 480-II real-time PCR platform using a high-stringency 18-cycle step-down temperature protocol without fluores- cence acquisition followed by 30 fluorescence acquisition cycles with a ...
Athletes and investigators remained blinded until the end of the data analysis. All study procedures were per- formed twice: before intervention (PRE) and immediately after four weeks of intervention (POST). The protocol was approved by the Independent Bioethics Commit- tee for Scientific Research ...