The virus-plasma mixture was removed after 1 h and 200 μl fresh growth medium was added to each well. The virus back-titration was included in each test. The plates were incubated for 5 days and the cytopathic effect was observed. The NAbs titers were calculated by using the Reed-...
The Upper Domail village, situated at an elevation of 2890 m above sea level (m a.s.l), had the highest average DFWD of 102.34 ± 8.8 kg hh−1. It was followed by Brithwar (2810 m a.s.l) with a consumption rate of 98.5 ± 7.5 kg hh−1, Leepa Valley-I (...
Since the virus possessing the abovementioned properties has been isolated, the cloning of a cDNA can be carried out in the following manner: the virus is precipitated from an appropriately large quantity of culture (about 1 l) and then taken up in phosphate-buffered sodium chloride solution. ...
Lorenz et al.158applied AF2 to predict the structure of selected KRAB159domains. They discovered an evolutionary conserved L-shaped body of two α-helices in all the domains of KRAB. It is changed into a typical spatial arrangement especially for mKRAB-AB after the replacement of amino acid a...
2, F and L). Celastrus/Celastrol Regulates Critical Immune Mediators of Bone Remodeling in Arthritic Rats To address the mechanisms underlying the observed effects of celastrus/celastrol on bone remodeling, we determined the effect of these natural products on the immune mediators of inflammation-...
Along this line it has been shown that mouse LCN2 (mLCN2) is overexpressed during the early stage of a bacterial infection (2) and that mLCN2-deficient mice are significantly more sensitive to bacterial infections (3). The physiological implications of the bacteriostatic properties of NGAL as ...
Abnormalities of the intestinal microbiota are implicated in the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), two spectra of inflammatory bowel disease (IBD). However, the high complexity and low inter-individual overlap of intestina
80Citations 123Altmetric Metrics Abstract Aging is a universal process that renders individuals vulnerable to many diseases. Although this process is irreversible, dietary modulation and caloric restriction are often considered to have antiaging effects. Dietary modulation can increase and maintain circulatin...
Adapters bind motor proteins to cargoes and therefore play essential roles in Kinesin-1 mediated intracellular transport. The regulatory mechanisms governing adapter functions and the spectrum of cargoes recognized by individual adapters remain poorly de
2006;291:L871–L879. 46. Becerril C, Pardo A, Montaño M, Ramos C, Ramírez R, Selman M. Acidic fibroblast growth factor induces an antifibrogenic phenotype in human lung fibroblasts. Am J Respir Cell Mol Biol. 1999;20: 1020–1027. 47. Shibuya M. Vascular endothelial ...