LIVER metastasisT cellsMELANOMABRAF genesRNA sequencingHYPOXEMIAMETASTASISPurpose: Uveal melanoma (UM) with BAP1 inactivating mutations has a high risk of metastasis, but the mechanism behind BAP1 deficiency driving UM metastasis is unknown. Methods: We analyzed the single-cell RNA sequencing (scRNA-...
ITGB2LFA-1Mac-1Background and Study Aims: Biliary atresia (BA) is a devastating disease of infants, invariably leading to cirrhosis, end-stage liver disease, and death if untreated. The etiology of BA is unknown, although infectious, immune, and genetic causes have been suggested. This study...