While less common, the most serious side effects of isosorbide mononitrate are described below, along with what to do if they happen. Low Blood Pressure (Hypotension).Isosorbide mononitrate may causelow blood pressure. Low blood pressure is more likely to occur if you have excessive sweating or ...
Isosorbide mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins. Each tablet, for oral administration, contains either 30 mg, 60 mg or 120 mg of isosorbide mononitrate in an ...
4 Side effects 5 Interactions 6 NotesUsesIsosorbide mononitrate is used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Research on Isosorbide mononitrate as a cervical ripener to reduce time at hospital to...
myocardial infarctionplasma levels25 patients with stable angina pectoris after acute myocardial infarction were given single and maintenance doses of isosorbide-5-mononitrate (IS-5-MN) in a controlled-release formulation. For evaluation of the efficacy of this treatment, a score based on exercise ...
Isosorbide mononitrate has been studied in experimental dogs. In one study, a dose of approximately 1–2 mg/kg PO to dogs subjected to transmyocardial direct current shock produced acute hemodynamic effects that lasted only 2 h. This dose when administered over days, however, resulted in a chro...
Isosorbide dinitrateundergoes extensive first-pass metabolism in the liver and is cleared at a rate of 2 to 4 L/minute with a serum half-life of about 1 hour. Isosorbide dinitrate's clearance is primarily by denitration to the 2-mononitrate (15 to 25%) and the 5-mononitrate (75 to 85%...
This randomized clinical trial examines treatment outcomes with isosorbide mononitrate and cilostazol in patients with symptomatic cerebral small vessel
基本信息 序号 10-24 药品名称 单硝酸异山梨酯缓释片 商品名 Imdur 英文名称 Isosorbide Mononitrate Sustained-release Tablets 规格 60mg 剂型 片剂(缓释片) 持证商 AstraZeneca UK Limited 备注1 欧盟上市(上市国家:英国;产地:英国) 备注2 英国上市名称: Isosorbide Mononitrate Extended release film coated tablet...
[Overview] Isosorbide Mononitrate is the common name of 1,4:3,6-dianhydro-D-sorbitol-5 mononitrate, also known as 5-isosorbide dinitrate. The major b..
Thirty-seven patients with chronic, stable angina pectoris were included in a randomized, double-blind cross-over study to assess the efficacy of once- and twice-daily dosage regimens of 60 mg isosorbide-5-mononitrate, in a controlied release formulation (5-ISMN Durules® Astra). After 2 wee...