Isosorbide mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both arteries and veins. Each tablet, for oral administration, contains either 30 mg, 60 mg or 120 mg of isosorbide mononitrate in an ...
Overview:Isosorbide mononitrate is a tablet taken to prevent chest pain from heart disease. It works by relaxing the blood vessels that deliver oxygen to the heart. Common side effects include headache and dizziness. Serious side effects are rare, but can include low blood pressure. Notify your ...
Reviews-on-treatmentElantan long (EL) is the only long-acting isosorbide mononitrate formulation based on a controlled membrane principle. 30% of the dose is available for immediate release and the remaining 70% is gradually released over time. After oral administration, isosorbide mononitrate EL ...
This randomized clinical trial examines treatment outcomes with isosorbide mononitrate and cilostazol in patients with symptomatic cerebral small vessel
Organic nitrate esters: Clinical use and mechanisms of actions 1991, Pharmacological Reviews Nitrates: Why and how should they be used today? - Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate 1990, European Journal of Clinical PharmacologyView...
When single 100-mg oral doses of atenolol were administered 2 hours before isosorbide dinitrate at a 10-mg dose no differences in the pharmacokinetics of isosorbide dinitrate or its mononitrates were observed. Clinical Studies BiDil or a combination of isosorbide dinitrate and hydralazine hydrochloride...