In this study, we investigated the potential therapeutic effect of extracellular vesicles (EVs) derived from human liver stem cells (HLSCs) in an in vivo model of IRI-AKI, which subsequently develops into CKD B Methods b : EVs were purified by ultracentrifugation and characterized in accordance ...
Quite the reverse, the amount of mitochondrial DNA, which is a strong pro-inflammatory agent, was higher in DS mitovesicles compared to controls, consistent with the reported neuroinflammatory phenotype in DS. B Methods b : EVs were isolated from murine and human DS and control brains using a...
However, further research is needed to fully understand the mechanisms and optimize the use of EVs in clinical settings.doi:10.1002/jev2.12444Journal of Extracellular Vesicles