In addition, higher serum bilirubin levels appear to play a role in the pathophysiology and severity of ischemic stroke [22]. In our study, we could not confirm other factors that have been postulated previously like sex [7] or hypertension [6]. The link between sex and post-stroke ...
Allicin exhibits various pharmacological activities and has been suggested to be beneficial in the treatment of stroke. However, the underlying mechanisms are largely unknown. Here, we confirmed that allicin protected the brain from cerebral injury, whic
1 Current ischemic stroke treatments aim at restoring blood flow by either intravenous thrombolysis, mechanical thrombectomy, or a combination of both.2 However, despite timely and successful recanalization of the occluded vessel, many patients show insufficient clinical improvement. This has been referred...
This chapter focuses on acute ischemic stroke: mechanisms, risk factors, clinical presentation, diagnostic evaluation, and treatment other than intravenous thrombolysis and mechanical thrombectomy, which are discussed in Chap. 8. The topics are arranged alphabetically. Ischemic stroke in pediatric patients ...
The effects of noncardiac surgery and anesthesia on patient hemodynamics (e.g., blood pressure) can play a fundamental role in the pathophysiology of perioperative cardiovascular complications. Whether a hypotension-avoidance or a hypertension-avoidance BP management strategy in the perioperative setting ...
Astrocytes play a key role in EAE pathophysiology by orchestrating in the CNS the inflammatory response of resident and peripheral immune cells and by suppress- ing remyelination. Glia. 2014; 62(3): 452–67. 42. Navarro A, Boveris A, Bández MJ, et al. Human brain c...
Defining the pathogenesis and pathophysiology of neonatal encephalopathy and cerebral palsy. Obstet Gynecol 2003; 102(3): 628–636. PubMed Google Scholar Vannucci RC . Cerebral carbohydrate and energy metabolism in perinatal hypoxic-ischemic brain damage. Brain Pathol 1992; 2(3): 229–234. ...
(This article belongs to the Special Issue Stroke: From Pathophysiology to Therapy)Download keyboard_arrow_down Browse Figures Versions Notes Abstract Purpose: This study aimed to investigate the accuracy and clinical significance of an artificial intelligence (AI)-based automated Alberta Stroke ...
The underlying pathophysiology of both forms of cardiomyopathy is different (i.e., atherosclerosis, inflammation or genetic) and this subsequently may influence the clinical characteristics, the course of the disease and the prognosis, and therefore the management of these patients. Previous studies have...
According to literature, the incidence of ischemic stroke in childhood is about 3 cases per 100,000 children per year [1]. Pediatric AIS still remains a serious medical problem. Detrimental outcomes include seizures, recurrent strokes or even death [1,2]. The pathophysiology and the impact of ...