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Is it OK to take Tylenol PM every night? Is it safe to regularly take Tylenol PM?It's not a good idea to take it long-term, according to our medical advisors. Tylenol PM contains two medications—the pain reliever acetaminophen and an antihistamine (diphenhydramine) to help with insomnia. ...
This rat study, as well as the lack of data overall, makes me cautious, and I think those with sensitive guts should avoid it just to be on the safe side. For everyone else, I doubt the small amounts found in food will cause a problem, but it might be best to avoid it if possib...