(1983). Islet amyloid in type-2 (non-insulin-dependent) diabetes is related to insulin. Diabetologia 24:342–346.Westermark P, Wilander E (1983) Islet amyloid in type 2 (non-insulin-dependent) diabetes is related to insulin. Diabetologia 24: 342–346...
To study whether insulin resistance in Type 2 (non-insulin-dependent) diabetes mellitus is due to a defect in the expression of the insulin-responsive glucose transporter gene (GLUT-4) in human skeletal muscle, we measured the level of GLUT-4 mRNA and (in some of the subjects) its protein...
Insulin resistance in non-insulin dependent (type II) and insulin dependent (type I) diabetes mellitus. Insulin resistance is a characteristic feature of non-insulin dependent diabetes mellitus (NIDDM) due to target tissue defects in insulin action. Abnormali... JM Olefsky,RR Revers,M Prince,....
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifactorial in origin with both genetic and environmental factors contributing to its development. A genome-wide screen for...
We tested the hypothesis that a particular immune activation profile might be correlated with insulin resistance in a general population. By measuring 43 markers of immune, endothelial, and coagulation activation, we have previously shown that five different immune activation profiles may be distinguished...
Intracellular eccDNA SORBS1circle expression was significantly enhanced in the high glucose and palmitate (HG/PA)-induced hepatocyte (HepG2 cell) insulin resistance model. Moreover, the upregulation of eccDNA SORBS1circle in the HG/PA-treated HepG2 cells was dependent on generation of apoptotic ...
Type 2 diabetes mellitus is associated with an exaggerated glucose dependent insulinotropic polypeptide response to oral glucose and mixed meals which is independent of any effect of obesity. 展开 关键词: Glucose dependent insulinotropic polypeptide Type 2 (non-insulin-dependent) diabetes mellitus normal ...
Low skeletal muscle mass is associated with insulin resistance and metabolic syndrome. Serum creatinine may serve as a surrogate marker of muscle mass, and a possible relationship between low serum creatinine and type 2 diabetes has recently been demonst
male mice have lower insulin sensitivity than female mice4and are more susceptible to high-fat diet (HFD) induced obesity and metabolic syndrome5. The sex-dependent glucose metabolism difference is commonly observed in both humans3,6,7and rodent animals4,8. However, the underlying mechanisms that...
Tubulointerstitial lesions in non-insulin dependent diabetes mellitus. Kidney Int. Suppl. 63, S191–S194 (1997). CAS PubMed Google Scholar Shimizu, M. et al. Long-term outcomes of Japanese type 2 diabetic patients with biopsy-proven diabetic nephropathy. Diabetes Care. 36(11), 3655–3662 ...