A. et al. An L-threonine transaldolase is required for L-threo-b-hydroxy-a-amino acid assembly during obafluorin biosynthesis. Nat. Commun. 8, 15935 doi: 10.1038/ncomms15935 (2017). Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and...
We tested whether CLEC14A could bind to sialyl Lewis X and other classes of acidic and neutral glycans through the Consortium for Functional Glycomics Protein–Glycan Interaction Core using a glycan array covering 609 different glycan structures unrelated to GAGs. CLEC14A-325 did not bind ...
For all class A Hsfs, the CTADs are acidic and enriched in proline, serine, threonine, glutamic acid, and aspartic acid residues. The function of Hsfs as transcription-activating proteins is evidently connected with short [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯...
Rapid turnover of TIRAP is also regulated by the action of the serine/threonine kinases IRAK1 and IRAK4, enzymes that are part of the myddosome. Phosphorylation occurs at Thr28, within PBM, which targets TIRAP for ubiquitination and degradation16. Here, we employed structural, biochemical, ...
The pKa of histidine is 6.0, so histidine is best at buffering at pH 6.0. The acidic amino acids have pKa's below histidine's, and the basic amino acids have
The amino acids are arranged in three types: polar and acidic, polar and basic, and non-polar and neutral. The solubility of the protein is determined... Learn more about this topic: Proteins Lesson for Kids: Definition ...
Krahn1,2 The serine/threonine kinase LKB1 regulates various cellular processes such as cell proliferation, energy homeostasis and cell polarity and is frequently downregulated in various tumours. Many downstream pathways controlled by LKB1 have been described but little is known about the upstream ...
Bottom right, acid hydrolysis of whole cement from microspheres yields an abundance of glycine, alanine, serine and threonine in addition to hydrophobic residues. Asterisks indicate residues that are abundant in individual components. motifs such as elastin and collagen. G-X and S-X dipeptide motifs...
shown in Fig.3b. Electrostatic potential analysis shows that in this group of multivalent interactors (Fig.4, right panel), binding partners recognize both histone tails and nucleosomal/linker DNA via two separate patches: acidic (interactions with tails) and basic (interactions with DNA). Here ...
Phosphorylation of threonine-19 of PSD-95 by GSK-3beta is required for PSD-95 mobilization and long-term depression. J. Neurosci. 33, 12122–12135 (2013). 56. Quintana, P. et al. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA...