Is there any treatment for inflammatory amyloidosis?doi:10.1016/j.jbspin.2010.09.001Béatrice BouvardCédric AnnweilerAgnès SalléOlivier BeauchetDaniel ChappardMaurice AudranErick LegrandRetour au numéro
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protein, mRNA, and BACE1 activity in the cerebrospinal fluid (CSF) have been reported to be increased in studies of AD6,7,8,9. Additionally, utilizing ELISAs that measure the absolute concentrations of analytes, we previously demonstrated that there is an increase in the ratio of sAPPβ/sAPP...
摘要: Treatment with the small interfering RNA patisiran preserves functional capacity and improves health status and quality of life in patients with transthyretin cardiac amyloidosis, according to data from the 12-month double-blind period of the ongoing APOLLO-B trial....
Consequently, robust amyloidosis and pathological changes start to develop at two months of age and reach near-maximal levels by the seventh month [28]. In order to assess the therapeutic potential of rh Bri2 BRICHOS R221E, we started treatment of AppNL-G-F mice at 9 months, and WT ...
Amyloidosis is not a form of cancer, butchemotherapyand anti-inflammatory agents have been shown to help to prevent harmful deposits from collecting in various tissues and organs. Peripheral blood stem cell transplantation is another possible treatment option. Stem cell transplantation involves high-dose...
Finally, medical treatment was not included in the prognostic models. Several reasons were taken into account: medications were registered close to the time of diagnosis and are subject to change over time, and their use is influenced by factors other than the disease itself, including patient tol...
The results emphasize the intervention on PI3K–Akt pathway by SFQX in the treatment of HF. However, there was a lack of experimental validation of our results, which was the main limitation of our study. Future clinical study should assess the efficacy and safety of SFQX in treating HF, ...
(MMSE) score of 24 or above, and had undergone a rs-fMRI scan were included in the study. Participants who had any neurodegenerative disorders, took medications commonly prescribed for the treatment of dementia (e.g. Namenda, Razadyne, Aricept), had learning disabilities, self-reported abusing ...