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The protein is unique to Kinetoplastida, localises to the nucleolus and its depletion via RNAi caused a severe growth defect. Loss of the protein resulted in a decrease of global translation and accumulation of rRNA processing intermediates for both the small and large ribosomal subunits. Only a ...
The Apps that we (@dwyl) are creating must be decentralised; there cannot be a single point of failure. Decentralisation is not just "philosophical" argument, as creative technologists we are directly responsible for the technology we create. The lives of billions of people are at stake if we...
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Toybrick 应用开发 硬件平台:手头有RK3399PROX核心板及配套底板。核心板标识:TB-RK3399ProX_CoreBoard_33102。底板标识:TB-RK3399PROX_MAINBOARD_33102。固件:刚从t.rock-chips.com指 ...
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, posing a serious public health challenge that necessitates the development of new therapeutics, therapies, and prevention methods. Among the various therapeutic approaches, interventi
Neointimal hyperplasia (IH) is a common vascular pathology that typically manifests in in-stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic switching is central to IH, both regulated by some microRNAs, yet the role of mi
Several other of the identified SB genes provide insight into sexually dimorphic traits ofA. disparisand include candidate genes that can be studied in the future; these are described below. Transcriptome data suggest a molecular background for why the two sexes of this species have distinct flight...
While our study has implicated miR-30 in the regulation of FA metabolism in ECs and coronary microvascular dysfunction in diabetes, there are several limitations of the current work. Our cell culture experiments utilized human umbilical vein endothelial cells (HUVECs) as a generic model of EC biol...
no survival benefit of nivolumab was observed in patients with chemo-resistant SCLC [14]. Clearly, there is a need to identify SCLC patients who might be sensitive to immunotherapy and achieve satisfactorily prolonged survival. The development of more effective combined therapies or targeted drugs is...