ApoA-I is the most abundant protein in HDL, accounting for approximately 70% of total protein mass, and maintains the structure and function of HDL [12]. Reconstituted HDL containing apoA-I increases cholesterol efflux [13], and improves insulin secretion and glucose clearance in diabetic mice ...
ApoA-I is the most abundant protein in HDL, accounting for approximately 70% of total protein mass, and maintains the structure and function of HDL [12]. Reconstituted HDL containing apoA-I increases cholesterol efflux [13], and improves insulin secretion and glucose clearance in diabetic mice ...
Fatty acid composition of total body lipid, phospholipid, and neutral lipid of whole snail and total lipid of their algal food were analyzed by capillary gas chromatography and gas chromatography-mass spectrometry. The most abundant fatty acids were C16:0, C18:0, C16:1w7, C18:1w9, C18:2w6...
Cellular reprogramming consists of the loss of differentiated cell identity followed by the acquisition of embryonic stem pluripotency, which can be achieved by the simultaneous expression of the transcription factors OCT4, SOX2, KLF4 and MYC (OSKM; in mice encoded byPou5f1,Sox2,Klf4andMyc, respect...
The most abundant monounsaturated fatty acid in the total lipid of the SCD1+/+ mice is eicosenate (C20:1n-9) (148 mg/g), which was decreased by greater than 90% in the SCD1−/− mice. The content of C20:1n-7 was decreased by 34% whereas that of C18:1n-9 was decreased by...
In many societies, the majority of adults regularly consume alcohol. However, only a small proportion develops alcohol addiction. Individuals at risk often show a high sensation-seeking/low-anxiety behavioural phenotype. Here we asked which role EF hand
2b). αESA is abundant in certain plants (e.g. bitter melon and tung tree)26 and was previously shown to suppress the growth of breast cancer cells in a manner reversible by antioxidants27. Others have suggested that αESA triggers apoptotic cell death28,29,30,31,32,33 although a role...
(Fig.4b). The most abundant FAs in AT EVs included PA (approximately 25% in both EV types), OA (18% and 13% in VAT and SAT EVs, respectively), SA (15% in both EV types), and DHA (5% in both EV types) (Supplementary Figure S7, see Additional File1). The sum of all PUFAs...
The true incidence of the various types of anaphylactic reactions is difficult to determine because these reactions are often spontaneous and unpredictable and are clinically similar to other acute reactions. Estimates of the incidence of the most commonly reported episodes are possible, however. In the...
Patients with EGFR mutations in non-small cell lung cancer (NSCLC) have been greatly benefited from gefitinib, however, the therapeutic has failed due to the presence of acquired resistance. In this study, we show that gefitinib significantly induces downregulation of Sterol Regulator Element Binding...