The scientists that identified THCP say that the presence of small amounts of THCP in some marijuana strains could explain why those strains seem more intoxicating to users than other strains containing similar or even higher levels of delta 9 THC. In the future, cannabis breeders will probably ...
Coloration genetics Cannabinoids, including delta-9-tetrahydrocannabinol (9-THC) and cannabidiol (CBD), and their associated metabolites were quantified in maternal urine samples collected mid-pregnancy and in children's urine samples collected at the age of five. Exposure to cannabis before and after...
that THC-O, aka THC-O-acetate, is not a naturally occurring cannabinoid, but rather a synthetic derivative. Nonetheless, it is a cannabinoid that acts upon cannabinoid receptors in your brain, producing effects similar to THC. In fact,research has foundit to be roughly 3xstronger than THC. ...
We have demonstrated that THC has little added value in combined-cannabinoid glioblastoma treatment, suggesting that this psychotropic cannabinoid should be replaced with CBG in future clinical studies of glioblastoma therapy. Keywords: apoptosis; cannabinoids; cannabigerol; cannabidiol...
However, the association of childhood abuse with DNAm was also stronger in five DMRs after further adjustment for mental health and lifetime trauma. Taken together, these mediation results are also consistent with chance. Our findings should be considered in light of important limitations. First, ...
The resultant luminescence intensities showed that an array of TF proteins (denoted as JUL1- interacting transcription factors [JiTFs]) from various TF families were able to interact with JUL1, among which 26 TFs showed especially strong interaction ability (more than 100-fold stronger when ...
Regarding Piezo1 fluorescence, the effect of Yoda1 was most evident on Piezo1 MFI and fluorescence in the dimple than in the rim, whatever the donor considered. Nevertheless, C1 systematically showed the most pronounced effect (Figure 3C,K–M; orange columns), as for spectrin membrane occupancy...
However, a role of PPARα in the regulation of cardiac genes other than the ones involved in fatty acid oxidation remains to be explored. Recent studies have shown that chronic activation of PPARα results in impaired contractile function, reduced mitochondrial respiration and increased coupling, ...