Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by insufficient insulin production due to the destruction of insulin secreting -cells in the Langerhans islets. A variety of factors, including chemicals, viruses, commensal bacteria and diet have been proposed to contribute to ...
Type 1 diabetes (T1D) is an autoimmune disease that often manifests during childhood and adolescence and is characterized by insulin deficiency resulting from destruction of pancreatic β cells1Over 2/3 of children with seroconversion to multiple islet autoantibodies (IA) progress to T1D within 10 ...
Type 1 diabetes mellitus (T1D) is an autoimmune disorder characterized by the destruction of insulin-producing ß-cells in the pancreas, resulting in a life-long dependence on exogenous insulin. T1D development is thought to be driven by both genetic and environmental influences, as genetic susc...
an autoimmune condition where the pancreas makes little or no insulin leading to high blood sugar levels, is often first diagnosed in childhood. This differs from type 2 diabetes, which is most often diagnosed in people 45 and older. The Centers for Disease Control and Prevention (CDC) estimate...
Type 1 diabetes (T1D) is an autoimmune disease that results from a deficient induction or maintenance of tolerance to islet 尾-cell antigens, allowing the ... Remi J. Creusot,N Giannoukakis,M Trucco,... - 《Diabetes》 被引量: 59发表: 2014年 Is it time to revisit our current hematopo...
Type 1 diabetes (T1D) arises from an autoimmune process where T cells target and destroy pancreatic beta cells. Islet transplantation, though a viable therapeutic option, is constrained by the quality and quantity of islets, and the concomitant need for immunosuppressive medications. Cutting-edge ...
Clinical pathologies draw us to envisage disease as either an independent entity or a diverse set of traits governed by common physiopathological mechanisms, prompted by environmental assaults throughout life. Autoimmune diseases are not an exception, gi
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the progressive loss of insulin-producing beta cells in the pancreas. Explain the relevance of enterovirus infection as a candidate trigger of T1D islet autoimmunity?
Recently, ITPR3 was shown to be associated with type 1 diabetes (T1D) in the Swedish population (Roach et al. 2006). T1D is an autoimmune disease with cellular and humoral immunological abnormalities (Atkinson and Ei- senbarth 2001) and characterized with destruction of pancreatic islet beta ...
Type 1diabetes(T1D) is often referred to as "juvenile diabetes." It is an autoimmune disorder in which the body'simmune responseattacks the insulin-producing cells of the pancreas, the result of which is a lifelong dependence on insulin replacement therapies. Certain gene markers are indicated ...