Biogenesis of iron-sulfur proteins in eukaryotes: a novel task of mitochondria that is inherited from bacteria. Biochim Biophys Acta 2000; 1459: 370-382.Muhlenhoff, U. & Lill, R. (2000) Biogenesis of iron-sulfur proteins in eukaryotes: a novel task of mitochondria that is inherited from ...
To interrogate this, we temporally assessed the function of Fe-S proteins in response to various insults to the Fe-S cluster synthesis pathway. In addition to limiting sulfur through starving cells of cystine, we restricted iron availability by chelating cellular iron with deferoxamine (DFO)41 or...
Whereas bacteria are very flexible in terms of their sulfur source, animals require dietary intake of sulfur-containing amino acids, such as methionine, which serves as a biosynthetic precursor of cysteine (2). In organisms, sulfur is present in proteins, nucleic acids, sulfate esters of ...
which is abundant in marine environments1,2. It is well known that sulfur-oxidizing bacteria include diverse autotrophic bacteria from various groups, such as SUP05, SAR324, BS-GSO2, and Chlorobi3. These bacteria employ thesoxmulti-enzyme...
Chemically, protein is composed ofamino acids, which are organic compounds made ofcarbon,hydrogen,nitrogen,oxygenorsulfur. Just as amino acids are the building blocks of proteins, proteins are the building blocks of muscle mass, according to theNational Institutes of Health(NIH). ...
Summary The cytoplasmic iron-sulfur assembly (CIA) targeting complex is required for the transfer of an iron-sulfur (Fe-S) cluster to cytoplasmic and nuclear proteins, but how it engages with client proteins is unknown. Here, we show that the complex members MIP18 and CIAO1 associate with ...
(NiFe)-hydrogenase Group 1b, large subunit; fccB: flavocytochrome c sulfide dehydrogenase; sqr: sulfide:quinone reductase; soxA, soxB, soxC: sulfur oxidation proteins; sorA: sulfite dehydrogenase; psrA: polysulfide reductase, subunit I; qoxB: cytochrome c oxidase, caa3-type, subunit I; ...
Crassulacean acid metabolism (CAM) is found in plants adapted to very hot and dry environments, such as cacti and pineapples, according to the Khan Academy. When stomata open to take in CO2, they risk losing water to the external environment. Because of this, plants in very arid and hot ...
In the second of the parallel pathways, the thiazole moiety of thiamine (4-methyl-5-(2-hydroxyethyl)-thiazole phosphate, HET-P) is synthesized from glycine, NAD+ and a sulfur donor protein, in a similar manner to the system utilized in yeast [7]. The major enzyme involved in the HET-...
The CC2748 gene, which encodes the putative sulfite oxidase subunit YedY, is another protein with a potential role in sulfur metabolism. All of the remaining σF-dependent genes (CC2905, CC2906, CC2907, CC3254, CC3255 and CC3256) code for proteins with conserved domains of unknown ...