Sigma males are no less than alpha males when it comes to leadership. However, the only minute difference is that Sigma males do not love to exercise their leadership powers. That's because they prefer to work independently without controlling (or being controlled by) others. 21. Adaptable Jus...
1d–f is only present in the flat-band limit when U is much larger than the bandwidth but comparable to the topological gap. Consequently, our theoretical work here is consistent with the sudden onset of the QAH state. Since the temperature for Fig. 1g–i is higher than the previous row...
Rate constants were determined from the time course of spectrum change (430 nm–415 nm) by fitting to exponential functions using SigmaPlot 10.0. Measurement of NO production by isolated vessels This experiment was performed according to the setup described previously in Totzeck et al43. Briefly...
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The mice were deeply anesthetized using tribromoethanol (Sigma-Aldrich, St. Louis, MO, USA). Blood was taken by removal eyeball and centrifuged at 1000 × g/min for 10 min at 4 °C to obtain plasma for measurement cytokines using the Bio-Plex Pro Mouse Cytokine Standard 23-Plex (Bi...
LDHA mRNA expression was higher in α-cells than β-cells in 4 out 5 analyzed human islet isolations (Fig. 1D). The two endocrine populations were validated by insulin and glucagon mRNA, which were almost exclusively expressed in β-cell and α-cell fractions, respectively, as shown before ...
Briefly, fresh RBCs (stored less than a week) were washed three times in cold PBS. Of this pellet, 64 mL packed RBCs were transferred to 128 mL of freshly prepared preloading lysis buffer (5 mM K2HPO4, 20 mM Glucose, pH 7.4) and 2 ...
In addition, untreated HGPS fibroblasts exhibit significantly higher proportion of speckles only staining (31%) and as well as negative staining (18%). All the drug treatments improved the HGPS cells with respect to lamin B2 by exhibiting a reduction in the fraction of lamin B2 speckle-only ...
This can intuitively be seen as testing whether a cell has a higher mean GMV activation than another, the expectation representing empirical frequency. We evaluate the most probable hypothesis by studying the log-Bayes factor K defined as: $$K={{{\mathrm{log}}}\,}_{e}\frac{p({{{\mathc...
In the hippocampus, NMDARs are heteromeric assemblies mainly composed of a constitutive GluN1 subunit and GluN2A or GluN2B subunits [55]. The deactivation time course of GluN1/GluN2B heteromers is higher than the one observed for GluN1/GluN2A heteromers [56]. To test if NMDAR overactivation...