Orthotopic tumor and sentinel lymph nodes (SLNs) were successfully resected in the operating room, guided by the NIR-II imaging window, minimizing ambient light interference. Remarkably, the SPC biosensor displayed 100% sensitivity and specificity for tumor markers, leading to fast and high-...
(DCs), showcasing an upregulation of pro-interleukin-1 and other genes essential to their sentinel function. Dendritic cells experience contact-dependent calcium shifts and membrane depolarization in response to nociceptor activation, resulting in increased production of pro-inflammatory cytokines during ...
Expansion of the MIREN network in the region is currently being facilitated through the Afromontane Research Unit of the University of the Free State at three sites ranging from montane to alpine elevations: Witsieshoek Pass and Sentinel trail, Cathedral Peak (Mike’s and Organ Pipes Passes), ...