A century ago, Kraepelin and Bleuler observed that schizophrenia is often antedated by "premorbid" abnormalities. In this study we explore how the childhood neurodevelopmental problems found in patients with schizophrenia relate to the current concept of autism spectrum disorder (ASD). Forty-six ...
Once thought to be the same disorder, autistic disorder and childhood schizophrenia were in the 1970s shown to be distinguishable by symptomatology and age of onset. However, as the concept of autism spectrum disorders (ASD) as well as that of schizophrenia spectrum disorders have evolved, the ...
M Pathania1, EC Davenport1, J Muir, DF Sheehan, G López-Doménech and JT Kittler Copy number variation (CNV) at the 15q11.2 region has been identified as a significant risk locus for neurological and neuropsychiatric conditions such as schizophrenia (SCZ) and autism spectrum disorder (ASD)....
The Autism-Spectrum Quotient (AQ) is among the most widely used scales assessing autistic traits in the general population. However, some aspects of the AQ are questionable. To test its scale properties, the AQ was translated into Swedish, and data were collected from 349 adults, 130 with au...
Identification of common genetic risk variants for autism spectrum disorder. Nat. Genet. 51, 431–444 (2019). Article CAS PubMed PubMed Central Google Scholar Sebat, J., Levy, D. L. & McCarthy, S. E. Rare structural variants in schizophrenia: one disorder, multiple mutations; one ...
Share on Facebook mental disorder (redirected fromWhat is Mental Illness?) Thesaurus Medical Related to What is Mental Illness?:Mental disorders mental disorder n. Any of various disorders, such as schizophrenia, bipolar disorder, or autism spectrum disorder, characterized by a distressing or disablin...
such as schizophrenia, autism spectrum disorders or Niemann-Pick disease8,9,10,11,12,13. The few animal studies so far performed indicate that the severity of the cerebellar abnormalities directly determine the extent to which cognition is affected14,15. Thus, due to the lack of time-course ...
There are numerous categories in the DSM-V, including Neurodevelopmental Disorders, Schizophrenia Spectrum and Other Psychotic Disorders, Bipolar and Related Disorders, Personality Disorders, and Depressive Disorders. Within these categories are several sub-categories. For example, under the category Neurodeve...
such as schizophrenia, autism spectrum disorders or Niemann-Pick disease8,9,10,11,12,13. The few animal studies so far performed indicate that the severity of the cerebellar abnormalities directly determine the extent to which cognition is affected14,15. Thus, due to the lack of time-course ...
Schizophrenia (SCZ) is a chronic mental illness and among the most debilitating conditions encountered in medical practice. A recent landmark SCZ study of the protein-coding regions of the genome identified a causal role for ten genes and a concentration