Biochemical studies suggest that reduction of β-lapachone by NQO1 leads to a futile cycling between the quinone and hydroquinone forms, with a concomitant loss of reduced NAD(P)H. In addition, the activation of a cysteine protease, which has characteristics consistent with the neutral calcium-...
Additionally, enhanced glycolysis could reduce the sensitivity of AML cells to the antileukemia drug arabinofuranosyl cytidine (Ara-C), while inhibition of glycolysis reduced AML cell proliferation and enhanced the cytotoxicity of Ara-C (Chen et al., 2014). B-ALL cells rely on glucose transporter...
The central feature of this process is the development of a cartilage template, known as the growth plate, which drives longitudinal growth through chondrocyte proliferation, hypertrophy, and ultimately differentiation into osteoblasts1,2,3,4,5,6,7,8. The timing of the transition from proliferation ...
In these experiments, efficient conversion of benzoyl-CoA to benzaldehyde was observed only in the presence of NADPH (Fig. 3a). No benzaldehyde was formed when benzoyl-CoA was replaced by benzoic acid or cinnamic acid or when NADH, NADP+, NAD+ were supplied instead of NADPH in reaction with...
An analogous phenotype was observed in the silencing of the gene encoding a mitochondrial NADP+-dependent malic enzyme. These results suggest that the reducing equivalents produced in glycolysis are shuttled to the mitochondria as malate, where cytosolic NAD+ regeneration is coupled with mitochondrial ...
nadp-dependent 154ydroxyprostaglandin deziydrogenase is homologous to nad-dependent 15-hydroxyprostaglandin dehydrogenase and other short-chain alcohol deh... B Wemuth 被引量: 0发表: 0年 Molecular cloning, overexpression, and characterization of steroid-inducible 3alpha-hydroxysteroid dehydrogenase/...
乐谱名:Nadpis Na Nadgrobe 作曲:暂无 歌手:Danilo Jr 音轨数:7 乐谱类型:未知 乐谱《Nadpis Na Nadgrobe》由琴友【牛头青年】上传分享,权益归制作者所有, 但最终的版权仍然是原曲作者或所属单位所有,如果您是原曲作者或所属单位你可以选择强制【下架此谱】或【与制谱者分享权益】。 上一首 下一首 贝斯...
(protongradi-iscalled“thermaldissipation”becauseexcessivelightentregulation),inwhichdownregulationofphotosys-energyissafelydissipatedasheatfromPSII,thereforetemIIphotochemistryinresponsetointenselightwasavoidingtheproductionoftripletchlorophyllsthatreactimpaired.PGR5encodesanovelthylakoidmembranewithmolecularoxygen.Thermal...
1C) with a predicted Rossman fold domain for NAD(P) binding and a predicted PNDO domain (49). A BLASTP search of NWMN2274 against the sequences from the Protein Data Bank found distantly related homologs (<35% amino acid sequence identity). These include a ferredoxin-NADP+ oxidoreductase...
Fontecave, Is the NAD(P)H:Flavin oxidoreductase from Escherichia coli a member of the ferredoxin-NADP+ reductase family?, The Journal of Biological Chemistry 271 (1996) 16656-16661.Niviere, V., F. Fieschi, J.-L. Decout, and M. Fontecave. 1996. Is the NAD- (P)H:flavin oxidoreductase...