It is important to note that the current study has potential limitations. For instance, both of our Nurr1-ablation strategies might lead to off-target deletion of the transcription factor in other brain regions, which could contribute to our results. Nurr1 expression is dynamic and has been ...
The RNA-primer mixture was then added with 4 μl of 5×reverse transcription reac- tion and buffer, 1 μl of I4m.8P μrloomf -2I5I mreMveMrsegCtrla2,n3s.c7r iμpltoafseD(EPPrCom-treegaat)e.dTwheatreera, c1t μiol nofw1a0s minMcudb...
Nanosecond pulsed electric fields (nsPEFs) induce changes in the plasma membrane (PM), including PM permeabilization (termed nanoporation), allowing free passage of ions into the cell and, in certain cases, cell death. Recent studies from our laboratory show that the composition of the PM is a...
of various matrix-degrading proteases, such as the activation of MMP-2 and MMP-9 (37,64). Although several studies have demonstrated that OPN and MMP-9 are implicated in the development and progression of several types of cancer (22,34,35,38,43,46,49–51,65), it is important to ...